Adapalene

Catalog No. A10038

Adapalene是一类RAR和RXR双重的激动剂，主要用于治疗痤疮。

Technical details

Catalog Num	A10038
M. Wt	412.5
Formula	C28H28O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	106685-40-9
Synonyms	Differin
SMILES	COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5

Biological Activity

Adapalene是一类RAR和RXR双重的激动剂，主要用于治疗痤疮。

Targets

RARγ	RARβ	RXR

Solubility *

In vitro	DMSO	7 mg/mL (16.97 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.24 mL	121.21 mL	242.42 mL
0.5 mM	4.85 mL	24.24 mL	48.48 mL
1 mM	2.42 mL	12.12 mL	24.24 mL
5 mM	0.48 mL	2.42 mL	4.85 mL

*The above data is based on the productmolecular weight 412.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.