Adefovir dipivoxil

Catalog No. A10039

Adefovir dipivoxil是口服的核苷酸类似物逆转录酶抑制剂（ntRTI）。

Product Citations

Kazumoto Murata, .et al. Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection, Gut, 2018, Feb; 67(2): 362-371 PMID: 27789659

Technical details

Catalog Num	A10039
M. Wt	501.5
Formula	C20H32N5O8P
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	142340-99-6
Synonyms	Bis-POM PMEA, Preveon, Hepsera
SMILES	CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C

Biological Activity

Adefovir dipivoxil是口服的核苷酸类似物逆转录酶抑制剂（ntRTI）。

Solubility *

In vitro	DMSO	85 mg/mL (169.5 mM)
	Water	Insoluble
	Ethanol	85 mg/mL (169.5 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.94 mL	99.7 mL	199.4 mL
0.5 mM	3.99 mL	19.94 mL	39.88 mL
1 mM	1.99 mL	9.97 mL	19.94 mL
5 mM	0.4 mL	1.99 mL	3.99 mL

*The above data is based on the productmolecular weight 501.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.