Adriamycin

Catalog No. A10041

Adriamycin是一种蒽环类抗生素,它通过插入DNA起作用,而最严重的副作用是危及生命的心脏损害。它通常用于治疗多种癌症,包括血液系统恶性肿瘤,多种类型的癌症和软组织肉瘤。
  • Sanaz Naghibi, .et al. Brush-like Polymer Prodrug with Aggregation-Induced Emission Features for Precise Intracellular Drug Tracking, Biosensors (Basel), 2022, May 29;12(6):373 PMID: 35735521
Catalog Num A10041
M. Wt 580.0
Formula C27H29NO11.HCl
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 25316-40-9
Synonyms Doxorubicin
SMILES C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Adriamycin是一种蒽环类抗生素,它通过插入DNA起作用,而最严重的副作用是危及生命的心脏损害。它通常用于治疗多种癌症,包括血液系统恶性肿瘤,多种类型的癌症和软组织肉瘤。
Targets
Topo II (Tumor cells)
In vitro DMSO Warmed: 88 mg/mL (151.72 mM)
Water 18 mg/mL (31.03 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.24 mL 86.21 mL 172.41 mL
0.5 mM 3.45 mL 17.24 mL 34.48 mL
1 mM 1.72 mL 8.62 mL 17.24 mL
5 mM 0.34 mL 1.72 mL 3.45 mL

*The above data is based on the productmolecular weight 580.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.