Tyrphostin AG 879

Catalog No. A10053

Tyrphostin AG 879是神经生长因子(NGF)TrkA酪氨酸激酶活性的抑制剂。
Catalog Num A10053
M. Wt 316.5
Formula C18H24N2OS
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 148741-30-4
Synonyms AG879
SMILES CC(C)(C)C1=CC(=C/C(=C(/N)\S)/C#N)C=C(C1=O)C(C)(C)C
Tyrphostin AG 879是神经生长因子(NGF)TrkA酪氨酸激酶活性的抑制剂。
Targets
HER2-Neu Trk PDGFR EGFR
1.0 μM10 μM>100 μM>500 μM
In vitro (25°C) DMSO 35 mg/mL (110.59 mM)
Water Insoluble
Ethanol 3 mg/mL (9.47 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.6 mL 157.98 mL 315.96 mL
0.5 mM 6.32 mL 31.6 mL 63.19 mL
1 mM 3.16 mL 15.8 mL 31.6 mL
5 mM 0.63 mL 3.16 mL 6.32 mL

*The above data is based on the productmolecular weight 316.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.