Tyrphostin AG 879
Catalog No. A10053
Tyrphostin AG 879是神经生长因子(NGF)TrkA酪氨酸激酶活性的抑制剂。
Catalog Num | A10053 |
---|---|
M. Wt | 316.5 |
Formula | C18H24N2OS |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 148741-30-4 |
Synonyms | AG879 |
SMILES | CC(C)(C)C1=CC(=C/C(=C(/N)\S)/C#N)C=C(C1=O)C(C)(C)C |
Tyrphostin AG 879是神经生长因子(NGF)TrkA酪氨酸激酶活性的抑制剂。
Targets
HER2-Neu | Trk | PDGFR | EGFR | |
1.0 μM | 10 μM | >100 μM | >500 μM |
In vitro (25°C) | DMSO | 35 mg/mL (110.59 mM) | |
Water | Insoluble | ||
Ethanol | 3 mg/mL (9.47 mM) | ||
In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 31.6 mL | 157.98 mL | 315.96 mL |
0.5 mM | 6.32 mL | 31.6 mL | 63.19 mL |
1 mM | 3.16 mL | 15.8 mL | 31.6 mL |
5 mM | 0.63 mL | 3.16 mL | 6.32 mL |
*The above data is based on the productmolecular weight 316.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.