Azacitidine(Vidaza)

Catalog No. A10105

Azacitidine (Vidaza)是DNA和RNA中使用的胞嘧啶核苷的化学类似物，主要用于治疗骨髓增生异常综合症（MDS）。

Technical details

Catalog Num	A10105
M. Wt	244.2
Formula	C8H12N4O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	320-67-2
Synonyms	5-azacytidine, Mylosar, Ladakamycin, Vidaza
SMILES	C1=NC(=NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N

Biological Activity

Azacitidine (Vidaza)是DNA和RNA中使用的胞嘧啶核苷的化学类似物，主要用于治疗骨髓增生异常综合症（MDS）。

Targets

DNA methyltransferase (Cell-free assay)

Solubility *

In vitro (25°C)	DMSO	Warmed: 45 mg/mL (184.28 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.95 mL	204.75 mL	409.5 mL
0.5 mM	8.19 mL	40.95 mL	81.9 mL
1 mM	4.1 mL	20.48 mL	40.95 mL
5 mM	0.82 mL	4.1 mL	8.19 mL

*The above data is based on the productmolecular weight 244.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.