AZD7762

Catalog No. A10113

AZD7762是一种有效的ATP竞争性检查点激酶抑制剂，可促进检查点废止并增强DNA靶向疗法。

Technical details

Catalog Num	A10113
M. Wt	362.4
Formula	C17H19FN4O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	860352-01-8
Synonyms	AZD-7762
SMILES	C1C[C@@H](CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N

Biological Activity

AZD7762是一种有效的ATP竞争性检查点激酶抑制剂，可促进检查点废止并增强DNA靶向疗法。

Targets

Chk1 (Cell-free assay)	Chk2 (Cell-free assay)
5 nM	<10 nM

Solubility *

In vitro	DMSO	50 mg/mL (137.96 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.59 mL	137.97 mL	275.94 mL
0.5 mM	5.52 mL	27.59 mL	55.19 mL
1 mM	2.76 mL	13.8 mL	27.59 mL
5 mM	0.55 mL	2.76 mL	5.52 mL

*The above data is based on the productmolecular weight 362.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.