Aztreonam (Azactam, Cayston)

Catalog No. A10118

Aztreonam (Azactam,Cayston)是一种合成的单环β-内酰胺抗生素 (一种单bactam)，其细胞核是基于一种从紫罗兰色杆菌中分离出来的更简单的单bactam。

Product Citations

Sreevalli Sharma, .et al. Azaindole Based Potentiator of Antibiotics against Gram-Negative Bacteria, ACS Infect Dis, 2021, Nov 12;7(11):3009-3024 PMID: 34699190
Pholwat S, .et al. Genotypic antimicrobial resistance assays for use on E. coli isolates and stool specimens, PLoS One, 2019, May 10;14(5):e0216747 PMID: 31075137
Robert Bucki, .et al. Targeting polyelectrolyte networks in purulent body fluids to modulate bactericidal properties of some antibiotics, Infect Drug Resist, 2018, 11: 77-86 PMID: 29391814

Technical details

Catalog Num	A10118
M. Wt	435.4
Formula	C13H17N5O8S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	78110-38-0
Synonyms	Monobactam, SQ 26776, Squibb 26776
SMILES	C[C@H]1[C@@H](C(=O)N1S(=O)(=O)O)NC(=O)/C(=N\OC(C)(C)C(=O)O)/C2=CSC(=N2)N

Biological Activity

Aztreonam (Azactam,Cayston)是一种合成的单环β-内酰胺抗生素 (一种单bactam)，其细胞核是基于一种从紫罗兰色杆菌中分离出来的更简单的单bactam。

Solubility *

In vitro	DMSO	84 mg/mL (192.91 mM)
	Water	11 mg/mL (25.26 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.97 mL	114.84 mL	229.67 mL
0.5 mM	4.59 mL	22.97 mL	45.93 mL
1 mM	2.3 mL	11.48 mL	22.97 mL
5 mM	0.46 mL	2.3 mL	4.59 mL

*The above data is based on the productmolecular weight 435.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.