Bleomycin sulfate

Catalog No. A10152

Bleomycin Sulfate硫酸博来霉素是一种糖肽类抗生素，也是一种鳞状细胞癌(SCC)抗癌剂。

Product Citations

Mai Kanemaru, .et al. Nanoparticle-mediated local delivery of pioglitazone attenuates bleomycin-induced skin fibrosis, J Dermatol Sci, 2018, Jan;93(1):41-49 PMID: 30655107

Technical details

Catalog Num	A10152
M. Wt	1512.6
Formula	C55H85N17O25S4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	9041-93-4
Synonyms	Blenoxane
SMILES	CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@H](C(=O)N)N)C(=O)N[C@@H](C(C2=CN=CN2)O[C@@H]3[C@@H]([C@@H]([C@H]([C@H](O3)CO)O)O)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)N[C@@H](C)[C@@H]([C@@H](C)C(=O)N[C@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O

Biological Activity

Bleomycin Sulfate硫酸博来霉素是一种糖肽类抗生素，也是一种鳞状细胞癌(SCC)抗癌剂。

Targets

UT-SCC-19A
4 nM

Solubility *

In vitro	DMSO	Warmed: 93 mg/mL (61.48 mM)
	Water	93 mg/mL (61.48 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	6.61 mL	33.06 mL	66.11 mL
0.5 mM	1.32 mL	6.61 mL	13.22 mL
1 mM	0.66 mL	3.31 mL	6.61 mL
5 mM	0.13 mL	0.66 mL	1.32 mL

*The above data is based on the productmolecular weight 1512.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.