BMS-794833

Catalog No. A10154

BMS-794833是Met和VEGFR-2的有效ATP竞争性抑制剂,IC50为1.7和15 nM。
Catalog Num A10154
M. Wt 468.8
Formula C23H15ClF2N4O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1174046-72-0
Synonyms BMS794833
SMILES C1=CC(=CC=C1C2=CNC=C(C2=O)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F)F
BMS-794833是Met和VEGFR-2的有效ATP竞争性抑制剂,IC50为1.7和15 nM。
Targets
Met VEGFR2
1.7 nM15 nM
In vitro DMSO 85 mg/mL (181.29 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.33 mL 106.66 mL 213.31 mL
0.5 mM 4.27 mL 21.33 mL 42.66 mL
1 mM 2.13 mL 10.67 mL 21.33 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.