Camptothecin

Catalog No. A10174

Camptothecin是一种细胞毒性喹啉生物碱，可抑制DNA酶拓扑异构酶I（拓扑I）。

Technical details

Catalog Num	A10174
M. Wt	348.4
Formula	C20H16N2O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	CAS:7689-03-4
Synonyms
SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O

Biological Activity

Camptothecin是一种细胞毒性喹啉生物碱，可抑制DNA酶拓扑异构酶I（拓扑I）。

Targets

Topo I (Cell-free assay)
0.68 μM

Solubility *

In vitro	DMSO	3 mg/mL (8.61 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.7 mL	143.51 mL	287.03 mL
0.5 mM	5.74 mL	28.7 mL	57.41 mL
1 mM	2.87 mL	14.35 mL	28.7 mL
5 mM	0.57 mL	2.87 mL	5.74 mL

*The above data is based on the productmolecular weight 348.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.