Carboplatin

Catalog No. A10182

Carboplatin是一种化学疗法药物，可用于治疗某些形式的癌症（主要是卵巢癌，肺癌，头颈癌）。顺铂和卡铂以及奥沙利铂与DNA相互作用，类似于烷基化剂的作用机理。

Product Citations

Jianwei Dou, .et al. Development and evaluation of poly adenosine 5'-diphosphate-ribose polymerase 1 immobilization-based receptor chromatography, J Sep Sci, 2020, Dec 4 PMID: 33275824

Technical details

Catalog Num	A10182
M. Wt	371.3
Formula	C6H12N2O4Pt
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	41575-94-4
Synonyms	Paraplatin
SMILES	C1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt]

Biological Activity

Targets

DNA synthesis (A2780, SKOV-3, IGROV-1, HX62 cells)

Solubility *

In vitro	DMSO	Insoluble
	Water	Warmed: 14 mg/mL (37.71 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.93 mL	134.66 mL	269.32 mL
0.5 mM	5.39 mL	26.93 mL	53.86 mL
1 mM	2.69 mL	13.47 mL	26.93 mL
5 mM	0.54 mL	2.69 mL	5.39 mL

*The above data is based on the productmolecular weight 371.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.