Cetirizine Dihydrochloride

Catalog No. A10195

Cetirizine Dihydrochloride是第二代抗组胺药，是羟嗪的主要代谢产物，是用于治疗过敏，花粉症，血管性水肿和荨麻疹的消旋选择性H1受体反向激动剂。

Technical details

Catalog Num	A10195
M. Wt	461.81
Formula	C21H25ClN2O3.2HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	83881-52-1
Synonyms
SMILES	C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl

Biological Activity

Cetirizine Dihydrochloride是第二代抗组胺药，是羟嗪的主要代谢产物，是用于治疗过敏，花粉症，血管性水肿和荨麻疹的消旋选择性H1受体反向激动剂。

Targets

Histamine receptor

Solubility *

In vitro	DMSO	81 mg/mL (175.39 mM)
	Water	81 mg/mL (175.39 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.65 mL	108.27 mL	216.54 mL
0.5 mM	4.33 mL	21.65 mL	43.31 mL
1 mM	2.17 mL	10.83 mL	21.65 mL
5 mM	0.43 mL	2.17 mL	4.33 mL

*The above data is based on the productmolecular weight 461.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.