Clemastine fumarate

Catalog No. A10226

Clemastine fumarate是一种选择性的组胺H1拮抗剂。它与组胺H1受体结合，从而阻断了内源性组胺的作用，从而暂时缓解了由组胺引起的阴性症状。

Technical details

Catalog Num	A10226
M. Wt	459.96
Formula	C21H26ClNO.C4H4O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	14976-57-9
Synonyms	meclastin
SMILES	C[C@@](C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCC[C@H]3CCCN3C.C(=C/C(=O)O)\C(=O)O

Biological Activity

Clemastine fumarate是一种选择性的组胺H1拮抗剂。它与组胺H1受体结合，从而阻断了内源性组胺的作用，从而暂时缓解了由组胺引起的阴性症状。

Targets

Histamine H1 receptor
3 nM

Solubility *

In vitro	DMSO	Warmed: 31 mg/mL (67.39 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.74 mL	108.71 mL	217.41 mL
0.5 mM	4.35 mL	21.74 mL	43.48 mL
1 mM	2.17 mL	10.87 mL	21.74 mL
5 mM	0.43 mL	2.17 mL	4.35 mL

*The above data is based on the productmolecular weight 459.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.