Clotrimazole

Catalog No. A10234

clotrimazole的作用是对抗真菌的分裂和生长。clotrimazole改变真菌细胞壁的通透性并抑制细胞内酶的活性。它特别抑制麦角固醇和细胞膜生产所需的其他固醇的生物合成。

Technical details

Catalog Num	A10234
M. Wt	344.84
Formula	C22H17ClN2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	23593-75-1
Synonyms
SMILES	C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4

Biological Activity

Targets

Solubility *

In vitro	DMSO	9 mg/mL (26.09 mM)
	Water	Insoluble
	Ethanol	59 mg/mL (171.09 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29 mL	144.99 mL	289.99 mL
0.5 mM	5.8 mL	29 mL	58 mL
1 mM	2.9 mL	14.5 mL	29 mL
5 mM	0.58 mL	2.9 mL	5.8 mL

*The above data is based on the productmolecular weight 344.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.