Daptomycin

Catalog No. A10289

Daptomycin是一种脂肽抗生素,用于治疗由革兰氏阳性生物体引起的某些感染。
  • Viktoria Lazar, .et al. Antibiotic combinations reduce Staphylococcus aureus clearance, Nature, 2022, 610: 540-546 PMID: 36198788
  • Shigeru Fujimura, .et al. Antimicrobial efficacy of combined clarithromycin plus daptomycin against biofilms-formed methicillin-resistant Staphylococcus aureus on titanium medical devices., J Infect Chemother., 2015, Oct;21(10):756-9 PMID: 26162777
Catalog Num A10289
M. Wt 1620.7
Formula C72H101N17O26
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 103060-53-3
Synonyms Cubicin
SMILES O=C([C@H](CC1=CNC2=CC=CC=C12)NC(CCCCCCCCC)=O)N[C@@H](C(N[C@H](C(N[C@@H]([C@@H](C)OC([C@]([H])(CC(C3=C(N)C=CC=C3)=O)NC([C@]([H])([C@@H](CC(O)=O)C)NC([C@@]([H])(CO)NC(CNC4=O)=O)=O)=O)=O)C(NCC(N[C@@H](CCCN)C(N[C@@]([H])(CC(O)=O)C(N[C@H](C)C(N[C@H]4CC(O)
Daptomycin是一种脂肽抗生素,用于治疗由革兰氏阳性生物体引起的某些感染。
Targets
DNA synthesis (Cell-free assay)
In vitro DMSO 87 mg/mL (53.68 mM)
Water Warmed: 87 mg/mL (53.68 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.17 mL 30.85 mL 61.7 mL
0.5 mM 1.23 mL 6.17 mL 12.34 mL
1 mM 0.62 mL 3.09 mL 6.17 mL
5 mM 0.12 mL 0.62 mL 1.23 mL

*The above data is based on the productmolecular weight 1620.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.