Disulfiram

Catalog No. A10320

Disulfiram是通过抑制乙醛脱氢酶来阻止体内酒精的加工，从而在消耗酒精时引起令人不快的反应。

Product Citations

Paul Mark Medina, .et al. Revealing the anticancer potential of candidate drugs in vivo using Caenorhabditis elegans mutant strains, Transl Oncol, 2021, Jan;14(1):100940 PMID: 33221682

Technical details

Catalog Num	A10320
M. Wt	296.54
Formula	C10H20N2S4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	97-77-8
Synonyms
SMILES	CCN(CC)C(=S)SSC(=S)N(CC)CC

Biological Activity

Disulfiram是通过抑制乙醛脱氢酶来阻止体内酒精的加工，从而在消耗酒精时引起令人不快的反应。

Targets

ALDH1

Solubility *

In vitro (25°C)	DMSO	58 mg/mL (195.59 mM)
	Water	Insoluble
	Ethanol	58 mg/mL
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.72 mL	168.61 mL	337.22 mL
0.5 mM	6.74 mL	33.72 mL	67.44 mL
1 mM	3.37 mL	16.86 mL	33.72 mL
5 mM	0.67 mL	3.37 mL	6.74 mL

*The above data is based on the productmolecular weight 296.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.