Docetaxel (Taxotere)

Catalog No. A10326

Docetaxel (Taxotere)多西他赛一种taxol类似物，是一种microtubules解聚抑制剂，通过结合于稳定的微管发挥作用。

Technical details

Catalog Num	A10326
M. Wt	807.9
Formula	C43H53NO14
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	114977-28-5
Synonyms	Taxotere
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Biological Activity

Docetaxel (Taxotere)多西他赛一种taxol类似物，是一种microtubules解聚抑制剂，通过结合于稳定的微管发挥作用。

Targets

Microtubules (Cell-free assay)

Solubility *

In vitro (25°C)	DMSO	92 mg/mL (113.88 mM)
	Water	Insoluble
	Ethanol	Warmed: 49 mg/mL (60.65 mM)
In vivo	5% DMSO+30% PEG 300+5% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.38 mL	61.89 mL	123.78 mL
0.5 mM	2.48 mL	12.38 mL	24.76 mL
1 mM	1.24 mL	6.19 mL	12.38 mL
5 mM	0.25 mL	1.24 mL	2.48 mL

*The above data is based on the productmolecular weight 807.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.