Donepezil hydrochloride

Catalog No. A10330

Donepezil hydrochloride是一种中枢可逆的乙酰胆碱酯酶抑制剂。
Catalog Num A10330
M. Wt 416
Formula C24H29NO3.HCl
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 120011-70-3
Synonyms
SMILES COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl
Donepezil hydrochloride是一种中枢可逆的乙酰胆碱酯酶抑制剂。
Targets
bAChE hAChE
8.12 nM11.6 nM
In vitro (25°C) DMSO Insoluble
Water 5 mg/mL (12.01 mM)
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.04 mL 120.19 mL 240.38 mL
0.5 mM 4.81 mL 24.04 mL 48.08 mL
1 mM 2.4 mL 12.02 mL 24.04 mL
5 mM 0.48 mL 2.4 mL 4.81 mL

*The above data is based on the productmolecular weight 416. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.