Dorzolamide HCL

Catalog No. A10333

Dorzolamide HCl是一种碳酸酐酶抑制剂。它是一种抗青光眼剂,以滴眼剂的形式局部使用。盐酸度尔佐胺用于降低开角型青光眼和高眼压患者的眼内压升高。
Catalog Num A10333
M. Wt 360.9
Formula C10H17ClN2O4S3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 130693-82-2
Synonyms Trusopt, Cosopt
SMILES CCN[C@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl
Dorzolamide HCl是一种碳酸酐酶抑制剂。它是一种抗青光眼剂,以滴眼剂的形式局部使用。盐酸度尔佐胺用于降低开角型青光眼和高眼压患者的眼内压升高。
Targets
Carbonic anhydrase II Carbonic anhydrase IV Carbonic anhydrase I
1.9 nM(Ki)31 nM(Ki)6000 nM(Ki)
In vitro DMSO Insoluble
Water 12 mg/mL (33.25 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.71 mL 138.54 mL 277.09 mL
0.5 mM 5.54 mL 27.71 mL 55.42 mL
1 mM 2.77 mL 13.85 mL 27.71 mL
5 mM 0.55 mL 2.77 mL 5.54 mL

*The above data is based on the productmolecular weight 360.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.