Flumazenil

Catalog No. A10397

Flumazenil是竞争性抑制GABA/苯二氮卓受体复合物上苯二氮卓识别位点的活性。Flumazenil在一些活性动物模型中是弱部分激动剂，但在人类中很少或没有激动剂活性。

Technical details

Catalog Num	A10397
M. Wt	303.3
Formula	C15H14FN3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	78755-81-4
Synonyms	Ro 15-1788
SMILES	CCOC(=O)c1ncn2c1CN(C)C(=O)c1c2ccc(c1)F

Biological Activity

Targets

GABAA receptor

Solubility *

In vitro	DMSO	4 mg/mL (13.18 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.97 mL	164.85 mL	329.71 mL
0.5 mM	6.59 mL	32.97 mL	65.94 mL
1 mM	3.3 mL	16.49 mL	32.97 mL
5 mM	0.66 mL	3.3 mL	6.59 mL

*The above data is based on the productmolecular weight 303.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.