Furosemide

Catalog No. A10412

Furosemide是GABAA受体的非竞争性拮抗剂，对含α6受体的选择性比含α1受体高约100倍。

Technical details

Catalog Num	A10412
M. Wt	330.74
Formula	C12H11ClN2O5S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	54-31-9
Synonyms	Lasix
SMILES	C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)O)S(=O)(=O)N)Cl

Biological Activity

Furosemide是GABAA受体的非竞争性拮抗剂，对含α6受体的选择性比含α1受体高约100倍。

Targets

NKCC2

Solubility *

In vitro	DMSO	63 mg/mL (190.48 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.24 mL	151.18 mL	302.35 mL
0.5 mM	6.05 mL	30.24 mL	60.47 mL
1 mM	3.02 mL	15.12 mL	30.24 mL
5 mM	0.6 mL	3.02 mL	6.05 mL

*The above data is based on the productmolecular weight 330.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.