Gatifloxacin

Catalog No. A10419

Gatifloxacin是一种氟喹诺酮类抗生素，可抑制细菌dna回旋酶(IC50 = 0.109 ng/ml)和拓扑异构酶iv(IC50 = 13.8 ng/ml)。

Technical details

Catalog Num	A10419
M. Wt	375.39
Formula	C19H22FN3O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	112811-59-3
Synonyms	AM 1155?? AM1155?? AM-1155
SMILES	CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F

Biological Activity

Gatifloxacin是一种氟喹诺酮类抗生素，可抑制细菌dna回旋酶(IC50 = 0.109 ng/ml)和拓扑异构酶iv(IC50 = 13.8 ng/ml)。

Targets

DNA gyrase	topoisomerase IV

Solubility *

In vitro	DMSO	7 mg/mL (18.64 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.64 mL	133.19 mL	266.39 mL
0.5 mM	5.33 mL	26.64 mL	53.28 mL
1 mM	2.66 mL	13.32 mL	26.64 mL
5 mM	0.53 mL	2.66 mL	5.33 mL

*The above data is based on the productmolecular weight 375.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.