GSK429286A
Catalog No. A10441
GSK429286A是含有蛋白激酶(ROCK)的Rho相关卷曲螺旋的细胞渗透性选择性小分子抑制剂。
Catalog Num | A10441 |
---|---|
M. Wt | 432.4 |
Formula | C21H16F4N4O2 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 864082-47-3 |
Synonyms | GSK-429286A |
SMILES | CC1=C(C(CC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=C(C=C4C(=C3)C=NN4)F |
GSK429286A是含有蛋白激酶(ROCK)的Rho相关卷曲螺旋的细胞渗透性选择性小分子抑制剂。
Targets
ROCK1 | ROCK2 | |||
14 nM | 63 nM |
In vitro (25°C) | DMSO | 81 mg/mL (187.33 mM) | |
Water | Insoluble | ||
Ethanol | 4 mg/mL (9.25 mM) | ||
In vivo | 15% Captisol+citrate vehicle | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.13 mL | 115.63 mL | 231.27 mL |
0.5 mM | 4.63 mL | 23.13 mL | 46.25 mL |
1 mM | 2.31 mL | 11.56 mL | 23.13 mL |
5 mM | 0.46 mL | 2.31 mL | 4.63 mL |
*The above data is based on the productmolecular weight 432.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.