Icariin
Catalog No. A10464
Icariin对抑制PDE5A1、PDE5A2和PDE5A3的所有三种PDE5A亚型均有抑制作用,IC50值分别为1.0、0.75和1.1 μM。
Catalog Num | A10464 |
---|---|
M. Wt | 676.7 |
Formula | C33H40O15 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 489-32-7 |
Synonyms | |
SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O |
Icariin对抑制PDE5A1、PDE5A2和PDE5A3的所有三种PDE5A亚型均有抑制作用,IC50值分别为1.0、0.75和1.1 μM。
Targets
PDE5 | ||||
0.432 μM |
In vitro | DMSO | 46 mg/mL (67.98 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 14.78 mL | 73.89 mL | 147.78 mL |
0.5 mM | 2.96 mL | 14.78 mL | 29.56 mL |
1 mM | 1.48 mL | 7.39 mL | 14.78 mL |
5 mM | 0.3 mL | 1.48 mL | 2.96 mL |
*The above data is based on the productmolecular weight 676.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.