Icariin

Catalog No. A10464

Icariin对抑制PDE5A1、PDE5A2和PDE5A3的所有三种PDE5A亚型均有抑制作用,IC50值分别为1.0、0.75和1.1 μM。
Catalog Num A10464
M. Wt 676.7
Formula C33H40O15
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 489-32-7
Synonyms
SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O
Icariin对抑制PDE5A1、PDE5A2和PDE5A3的所有三种PDE5A亚型均有抑制作用,IC50值分别为1.0、0.75和1.1 μM。
Targets
PDE5
0.432 μM
In vitro DMSO 46 mg/mL (67.98 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.78 mL 73.89 mL 147.78 mL
0.5 mM 2.96 mL 14.78 mL 29.56 mL
1 mM 1.48 mL 7.39 mL 14.78 mL
5 mM 0.3 mL 1.48 mL 2.96 mL

*The above data is based on the productmolecular weight 676.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.