JNJ 26854165

Catalog No. A10491

JNJ-26854165是P53激活剂之一,与AraC或阿霉素协同作用,诱导P53介导的凋亡,可能为急性白血病的治疗提供新的治疗途径。
  • Chang SJ, .et al. Proteomic investigating the cooperative lethal effect of EGFR and MDM2 inhibitors on ovarian carcinoma, Arch Biochem Biophys, 2018, Jun 1;647:10-32 PMID: 29655550
Catalog Num A10491
M. Wt 328.4
Formula C21H20N4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 881202-45-5
Synonyms JNJ26854165, JNJ-26854165
SMILES C1=CC=C2C(=C1)C(=CN2)CCNC3=CC=C(C=C3)NC4=CC=NC=C4
JNJ-26854165是P53激活剂之一,与AraC或阿霉素协同作用,诱导P53介导的凋亡,可能为急性白血病的治疗提供新的治疗途径。
In vitro (25°C) DMSO 56 mg/mL (170.51 mM)
Water Insoluble
Ethanol 2 mg/mL (6.08 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.45 mL 152.25 mL 304.51 mL
0.5 mM 6.09 mL 30.45 mL 60.9 mL
1 mM 3.05 mL 15.23 mL 30.45 mL
5 mM 0.61 mL 3.05 mL 6.09 mL

*The above data is based on the productmolecular weight 328.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.