Lamivudine

Catalog No. A10512

Lamivudine是一种有效的核苷类似物逆转录酶抑制剂(nRTI)。

Product Citations

Masaaki Toyama, .et al. Novel Neplanocin A Derivatives as Selective Inhibitors of Hepatitis B Virus with a Unique Mechanism of Action, Antimicrob Agents Chemother, 2022, Jun 21;66(6) PMID: 35604213
Toyama M, .et al. Pyrimidotriazine derivatives as selective inhibitors of HBV capsid assembly, Virus Res, 2019, Oct 2;271:197677 PMID: 31376401

Technical details

Catalog Num	A10512
M. Wt	229.25
Formula	C8H11N3O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	134678-17-4
Synonyms
SMILES	C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N

Biological Activity

Lamivudine是一种有效的核苷类似物逆转录酶抑制剂(nRTI)。

Targets

Reverse transcriptase

Solubility *

In vitro	DMSO	39 mg/mL (170.11 mM)
	Water	39 mg/mL (170.11 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	43.62 mL	218.1 mL	436.21 mL
0.5 mM	8.72 mL	43.62 mL	87.24 mL
1 mM	4.36 mL	21.81 mL	43.62 mL
5 mM	0.87 mL	4.36 mL	8.72 mL

*The above data is based on the productmolecular weight 229.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.