Lomustine (CeeNU)

Catalog No. A10535

Lomustine是一种烷基化亚硝脲化合物，具有类似于卡莫司汀的抗肿瘤活性，可引起DNA间交联。

Technical details

Catalog Num	A10535
M. Wt	233.69
Formula	C9H16ClN3O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	13010-47-4
Synonyms
SMILES	C1CCC(CC1)NC(=O)N(CCCl)N=O

Biological Activity

Lomustine是一种烷基化亚硝脲化合物，具有类似于卡莫司汀的抗肿瘤活性，可引起DNA间交联。

Targets

Solubility *

In vitro (25°C)	DMSO	40 mg/mL (171.16 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W, pH 4	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	42.79 mL	213.96 mL	427.92 mL
0.5 mM	8.56 mL	42.79 mL	85.58 mL
1 mM	4.28 mL	21.4 mL	42.79 mL
5 mM	0.86 mL	4.28 mL	8.56 mL

*The above data is based on the productmolecular weight 233.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.