MK 3207 HCl

Catalog No. A10598

MK 3207 hydrochloride是一种有效的CGRP受体拮抗剂,IC50为0.12 nM。
  • Marlene Dallmayer, .et al. Targeting the CALCB/RAMP1-axis inhibits growth of Ewing sarcoma, bioRxiv, 2018, 2018
Catalog Num A10598
M. Wt 594.1
Formula C31H30ClF2N5O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 957116-20-0
Synonyms MK3207, MK-3207
SMILES C1CCC2(C1)C(=O)N([C@@H](CN2)C3=CC(=CC(=C3)F)F)CC(=O)NC4=CC5=C(C[C@@]6(C5)C7=C(NC6=O)N=CC=C7)C=C4.Cl
MK 3207 hydrochloride是一种有效的CGRP受体拮抗剂,IC50为0.12 nM。
Targets
CGRP
0.12 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.83 mL 84.16 mL 168.32 mL
0.5 mM 3.37 mL 16.83 mL 33.66 mL
1 mM 1.68 mL 8.42 mL 16.83 mL
5 mM 0.34 mL 1.68 mL 3.37 mL

*The above data is based on the productmolecular weight 594.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.