NVP-BEP800

Catalog No. A10660

NVP-BEP800是一种新型的,完全合成的,口服可生物利用的抑制剂,可与Hsp90的NH2末端ATP结合袋结合。
  • Hiroki Murano, .et al. A purine-type heat shock protein 90 inhibitor promotes the heat shock response in Arabidopsis, Plant Biotechnol Rep, 2017, 11:107-113
Catalog Num A10660
M. Wt 480.4
Formula C21H23Cl2N5O2S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 847559-80-2
Synonyms VER-82576
SMILES CCNC(=O)C1=CC2=C(N=C(N=C2S1)N)C3=CC(=C(C=C3Cl)Cl)OCCN4CCCC4
NVP-BEP800是一种新型的,完全合成的,口服可生物利用的抑制剂,可与Hsp90的NH2末端ATP结合袋结合。
Targets
HSP90β
58 nM
In vitro (25°C) DMSO Insoluble
Water Insoluble
Ethanol 13 mg/mL (27.06 mM)
In vivo 0.5% methylcellulose 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.82 mL 104.08 mL 208.16 mL
0.5 mM 4.16 mL 20.82 mL 41.63 mL
1 mM 2.08 mL 10.41 mL 20.82 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 480.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.