Oligomycin A

Catalog No. A10669

Oligomycin A是线粒体ATPase抑制剂。寡霉素A抑制与细胞膜结合的ATP5（线粒体ATP酶，F1F0）。

Product Citations

Makoto Kawatani, .et al. Identification of a Small-Molecule Glucose Transporter Inhibitor, Glutipyran, That Inhibits Cancer Cell Growth, ACS Chem Biol, 2021, 16, 8, 1576-1586

Technical details

Catalog Num	A10669
M. Wt	791.06
Formula	C45H74O11
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	579-13-5
Synonyms
SMILES	CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C

Biological Activity

Oligomycin A是线粒体ATPase抑制剂。寡霉素A抑制与细胞膜结合的ATP5（线粒体ATP酶，F1F0）。

Targets

ATP synthase (Cell-free assay)

Solubility *

In vitro (25°C)	DMSO	9 mg/mL (11.38 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.64 mL	63.21 mL	126.41 mL
0.5 mM	2.53 mL	12.64 mL	25.28 mL
1 mM	1.26 mL	6.32 mL	12.64 mL
5 mM	0.25 mL	1.26 mL	2.53 mL

*The above data is based on the productmolecular weight 791.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.