Orlistat

Catalog No. A10676

Orlistat是一种一般的脂肪酶抑制剂，对人十二指肠液的PL的IC50为122 ng / ml。

Product Citations

M Sugihara, .et al. The AAA+ ATPase/ubiquitin ligase mysterin stabilizes cytoplasmic lipid droplets, J Cell Biol, 2019, pii: jcb.201712120 PMID: 30705059

Technical details

Catalog Num	A10676
M. Wt	495.73
Formula	C29H53NO5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	96829-58-2
Synonyms	Tetrahydrolipstatin
SMILES	CCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O

Biological Activity

Orlistat是一种一般的脂肪酶抑制剂，对人十二指肠液的PL的IC50为122 ng / ml。

Solubility *

In vitro (25°C)	DMSO	97 mg/mL (195.67 mM)
	Water	Insoluble
	Ethanol	97 mg/mL (195.67 mM)
In vivo	5% DMSO+40% PEG 300+5% Tween 80+ddH2O	12 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.17 mL	100.86 mL	201.72 mL
0.5 mM	4.03 mL	20.17 mL	40.34 mL
1 mM	2.02 mL	10.09 mL	20.17 mL
5 mM	0.4 mL	2.02 mL	4.03 mL

*The above data is based on the productmolecular weight 495.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.