PD153035 (HCl salt)

Catalog No. A10702

PD153035 (HCl salt)是EGFR酪氨酸激酶活性的极其有效和特异的抑制剂。
Catalog Num A10702
M. Wt 396.7
Formula C16H14BrN3O2.HCl
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 183322-45-4
Synonyms ZM 252868, AG 1517, Tyrphostin AG 1517, SU 5271, PD-153035
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl
PD153035 (HCl salt)是EGFR酪氨酸激酶活性的极其有效和特异的抑制剂。
Targets
EGFR (Cell-free assay) EGFR (Cell-free assay)
5.2 pM(Ki)5.2 pM(Ki)
In vitro (25°C) DMSO 0.46 mg/mL (1.16 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.21 mL 126.04 mL 252.08 mL
0.5 mM 5.04 mL 25.21 mL 50.42 mL
1 mM 2.52 mL 12.6 mL 25.21 mL
5 mM 0.5 mL 2.52 mL 5.04 mL

*The above data is based on the productmolecular weight 396.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.