PD318088

Catalog No. A10704

PD318088是MEK1和MEK2的抑制剂。

Technical details

Catalog Num	A10704
M. Wt	561.1
Formula	C16H13BrF3IN2O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	391210-00-7
Synonyms	PD-318088
SMILES	C1=CC(=C(C=C1I)F)NC2=C(C(=C(C=C2C(=O)NOCC(CO)O)Br)F)F

Biological Activity

PD318088是MEK1和MEK2的抑制剂。

Targets

MEK1/2

Solubility *

In vitro	DMSO	105 mg/mL (187.13 mM)
	Water	Insoluble
	Ethanol	13 mg/mL (23.17 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.82 mL	89.11 mL	178.22 mL
0.5 mM	3.56 mL	17.82 mL	35.64 mL
1 mM	1.78 mL	8.91 mL	17.82 mL
5 mM	0.36 mL	1.78 mL	3.56 mL

*The above data is based on the productmolecular weight 561.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.