Pimobendan (Vetmedin)

Catalog No. A10733

Pimobendan (Vetmedin)是一种钙增敏剂,具有正性肌力和血管舒张作用。它也是磷酸二酯酶III(PDE3)的选择性抑制剂。
Catalog Num A10733
M. Wt 334.4
Formula C19H18N4O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 74150-27-9
Synonyms Vetmedin, Acardi, pimobendane
SMILES CC1CC(=O)NN=C1C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)OC
Pimobendan (Vetmedin)是一种钙增敏剂,具有正性肌力和血管舒张作用。它也是磷酸二酯酶III(PDE3)的选择性抑制剂。
Targets
PDE3
0.32 μM
In vitro (25°C) DMSO 62 mg/mL (185.42 mM)
Water Insoluble
Ethanol 5 mg/mL (14.95 mM)
In vivo 0.5% methylcellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.9 mL 149.52 mL 299.04 mL
0.5 mM 5.98 mL 29.9 mL 59.81 mL
1 mM 2.99 mL 14.95 mL 29.9 mL
5 mM 0.6 mL 2.99 mL 5.98 mL

*The above data is based on the productmolecular weight 334.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.