Resveratrol

Catalog No. A10785

Resveratrol具有广泛的靶标，包括环氧合酶（COX，IC50 = 1.1μM），脂氧合酶（LOX，IC50 = 2.7μM），激酶，sirtuins和其他蛋白质。它具有抗癌，抗炎，降低血糖和其他有益的心血管作用。

Product Citations

Ha T. Tran, .et al. Resveratrol ameliorates the chemical and microbial induction of inflammation and insulin resistance in human placenta, adipose tissue and skeletal muscle, PLoS One, 2017, 12(3): e0173373 PMID: 28278187

Technical details

Catalog Num	A10785
M. Wt	228.2
Formula	C14H12O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	501-36-0
Synonyms
SMILES	C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O

Biological Activity

Targets

Target	Value
SIRT1
SIRT2
Quinonereductase2	IC50: 35nM-50nM
IKKβ	IC50: 1μM
DNApolymeraseα	IC50: 3.3μM
LOX	IC50: 3.7μM
DNApolymeraseδ	IC50: 5μM
COX	IC50: 15μM

Solubility *

In vitro (25°C)	DMSO	Warmed: 43 mg/mL (188.4 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+ddH2O	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	43.82 mL	219.11 mL	438.21 mL
0.5 mM	8.76 mL	43.82 mL	87.64 mL
1 mM	4.38 mL	21.91 mL	43.82 mL
5 mM	0.88 mL	4.38 mL	8.76 mL

*The above data is based on the productmolecular weight 228.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.