Telatinib (BAY 57-9352)

Catalog No. A10903

Telatinib (BAY 57-9352)是一种口服的血管内皮生长因子受体2和3(VEGFR2/3)和血小板衍生的生长因子受体β酪氨酸激酶的小分子抑制剂,IC50分别为6 nM/4 nM,1 nM和15 nM。
Catalog Num A10903
M. Wt 409.8
Formula C20H16ClN5O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 332012-40-5
Synonyms BAY57-9352
SMILES CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl
Telatinib (BAY 57-9352)是一种口服的血管内皮生长因子受体2和3(VEGFR2/3)和血小板衍生的生长因子受体β酪氨酸激酶的小分子抑制剂,IC50分别为6 nM/4 nM,1 nM和15 nM。
Targets
c-Kit VEGFR3 VEGFR2 PDGFRα
1 nM4 nM6 nM15 nM
In vitro DMSO 71 mg/mL (173.24 mM)
Water Insoluble
Ethanol 1 mg/mL (2.44 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.4 mL 122.01 mL 244.02 mL
0.5 mM 4.88 mL 24.4 mL 48.8 mL
1 mM 2.44 mL 12.2 mL 24.4 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.