Trilostane

Catalog No. A10949

Trilostane是用于治疗Cushing综合征的3β-羟基类固醇脱氢酶的抑制剂。

Technical details

Catalog Num	A10949
M. Wt	329.43
Formula	C20H27NO3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	13647-35-3
Synonyms	WIN24540, DB01108, Modrefen, Modrenal, Vetoryl
SMILES	N#CC1=C(O)[C@@]2([H])O[C@@]23[C@]([C@@]4([H])CC[C@@]5(C)[C@](CC[C@@H]5O)([H])[C@]4([H])CC3)(C)C1

Biological Activity

Trilostane是用于治疗Cushing综合征的3β-羟基类固醇脱氢酶的抑制剂。

Targets

3 β-hydroxysteroid dehydrogenase

Solubility *

In vitro	DMSO	63 mg/mL (191.24 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.36 mL	151.78 mL	303.55 mL
0.5 mM	6.07 mL	30.36 mL	60.71 mL
1 mM	3.04 mL	15.18 mL	30.36 mL
5 mM	0.61 mL	3.04 mL	6.07 mL

*The above data is based on the productmolecular weight 329.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.