Tubacin
Catalog No. A10954
Tubacin (tubulin acetylation inducer)是一种高效且选择性强,可逆,可透过细胞的HDAC6抑制剂,IC50为4 nM。
Catalog Num | A10954 |
---|---|
M. Wt | 721.9 |
Formula | C41H43N3O7S |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 537049-40-4 |
Synonyms | |
SMILES | C1[C@@H](O[C@@H](O[C@@H]1C2=CC=C(C=C2)CO)C3=CC=C(C=C3)NC(=O)CCCCCCC(=O)NO)CSC4=NC(=C(O4)C5=CC=CC=C5)C6=CC=CC=C6 |
Tubacin (tubulin acetylation inducer)是一种高效且选择性强,可逆,可透过细胞的HDAC6抑制剂,IC50为4 nM。
Targets
HDAC6 (Cell-free assay) | ||||
4 nM |
In vitro (25°C) | DMSO | 93 mg/mL (128.83 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 13.85 mL | 69.26 mL | 138.52 mL |
0.5 mM | 2.77 mL | 13.85 mL | 27.7 mL |
1 mM | 1.39 mL | 6.93 mL | 13.85 mL |
5 mM | 0.28 mL | 1.39 mL | 2.77 mL |
*The above data is based on the productmolecular weight 721.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.