CCT128930

Catalog No. A11031

CCT128930是一种具有ATP竞争性的AKT抑制剂，是一种有效的高级吡咯并嘧啶铅化合物，相对于PKA表现出对AKT的选择性，可通过靶向单个氨基酸差异实现。

Technical details

Catalog Num	A11031
M. Wt	341.8
Formula	C18H20ClN5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	885499-61-6
Synonyms	CCT-128930
SMILES	C1CN(CCC1(CC2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4

Biological Activity

CCT128930是一种具有ATP竞争性的AKT抑制剂，是一种有效的高级吡咯并嘧啶铅化合物，相对于PKA表现出对AKT的选择性，可通过靶向单个氨基酸差异实现。

Targets

Akt2 (Cell-free assay)	p70 S6K (Cell-free assay)	PKA (Cell-free assay)
6 nM	120 nM	168 nM

Solubility *

In vitro (25°C)	DMSO	59 mg/mL (172.59 mM)
	Water	Insoluble
	Ethanol	5 mg/mL (14.63 mM)
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.26 mL	146.28 mL	292.57 mL
0.5 mM	5.85 mL	29.26 mL	58.51 mL
1 mM	2.93 mL	14.63 mL	29.26 mL
5 mM	0.59 mL	2.93 mL	5.85 mL

*The above data is based on the productmolecular weight 341.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.