PHT-427

Catalog No. A11032

PHT-427是一种新型的Akt/磷脂酰肌醇依赖性蛋白激酶1 pleckstrin同源域抑制剂。

Technical details

Catalog Num	A11032
M. Wt	409.6
Formula	C20H31N3O2S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1191951-57-1
Synonyms	PHT427
SMILES	CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2

Biological Activity

PHT-427是一种新型的Akt/磷脂酰肌醇依赖性蛋白激酶1 pleckstrin同源域抑制剂。

Targets

Akt	PDK-1
2.7 μM(Ki)	5.2 μM(Ki)

Solubility *

In vitro (25°C)	DMSO	75 mg/mL (183.1 mM)
	Water	Insoluble
	Ethanol	55 mg/mL (134.27 mM)
In vivo	5% DMSO+95% Corn oil	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.41 mL	122.07 mL	244.14 mL
0.5 mM	4.88 mL	24.41 mL	48.83 mL
1 mM	2.44 mL	12.21 mL	24.41 mL
5 mM	0.49 mL	2.44 mL	4.88 mL

*The above data is based on the productmolecular weight 409.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.