ICG-001
Catalog No. A11039
ICG-001是Wnt/β-catenin信号传导途径的特异性抑制剂,可抑制β-catenin/环状AMP响应元件结合(CREB)蛋白的转录(IC50 = 3 uM)。
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Catalog Num | A11039 |
---|---|
M. Wt | 548.6 |
Formula | C33H32N4O4 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 780757-88-2 |
Synonyms | ICG001 |
SMILES | C1CN([C@H]2CN(C(=O)[C@@H](N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6 |
ICG-001是Wnt/β-catenin信号传导途径的特异性抑制剂,可抑制β-catenin/环状AMP响应元件结合(CREB)蛋白的转录(IC50 = 3 uM)。
Targets
CBP (Cell-free assay) | ||||
3 μM |
In vitro (25°C) | DMSO | 99 mg/mL (180.45 mM) | |
Water | Insoluble | ||
Ethanol | 10 mg/mL | ||
In vivo | 2% DMSO+50% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.23 mL | 91.14 mL | 182.28 mL |
0.5 mM | 3.65 mL | 18.23 mL | 36.46 mL |
1 mM | 1.82 mL | 9.11 mL | 18.23 mL |
5 mM | 0.36 mL | 1.82 mL | 3.65 mL |
*The above data is based on the productmolecular weight 548.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.