ICG-001

Catalog No. A11039

ICG-001是Wnt/β-catenin信号传导途径的特异性抑制剂,可抑制β-catenin/环状AMP响应元件结合(CREB)蛋白的转录(IC50 = 3 uM)。
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Catalog Num A11039
M. Wt 548.6
Formula C33H32N4O4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 780757-88-2
Synonyms ICG001
SMILES C1CN([C@H]2CN(C(=O)[C@@H](N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6
ICG-001是Wnt/β-catenin信号传导途径的特异性抑制剂,可抑制β-catenin/环状AMP响应元件结合(CREB)蛋白的转录(IC50 = 3 uM)。
Targets
CBP (Cell-free assay)
3 μM
In vitro (25°C) DMSO 99 mg/mL (180.45 mM)
Water Insoluble
Ethanol 10 mg/mL
In vivo 2% DMSO+50% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.23 mL 91.14 mL 182.28 mL
0.5 mM 3.65 mL 18.23 mL 36.46 mL
1 mM 1.82 mL 9.11 mL 18.23 mL
5 mM 0.36 mL 1.82 mL 3.65 mL

*The above data is based on the productmolecular weight 548.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.