URB597

Catalog No. A11049

URB597是脂肪酸酰胺水解酶(FAAH)的相对选择性抑制剂。
  • Lakhan S Khara, .et al. Inhibiting the endocannabinoid degrading enzymes FAAH and MAGL during zebrafish embryogenesis alters sensorimotor function, J Exp Biol, 2022, May 1;225(9):jeb244146 PMID: 35438163
  • Md Shah Sufian, .et al. Early suppression of the endocannabinoid degrading enzymes FAAH and MAGL alters locomotor development in zebrafish, J Exp Biol, 2021, 21 JUNE
  • Toshihiko Tsutsumi, .et al. Identification of human glycerophosphodiesterase 3 as an ecto phospholipase C that converts the G protein-coupled receptor 55 agonist lysophosphatidylinositol to bioactive monoacylglycerols in cultured mammalian cells, Biochim Biophys Acta Mol Cell Biol Lipids, 2020, Sep;1865(9):158761 PMID: 32629025
Catalog Num A11049
M. Wt 338.4
Formula C20H22N2O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 546141-08-6
Synonyms KDS-4103, URB-597
SMILES C1CCC(CC1)NC(=O)OC2=CC=CC(=C2)C3=CC(=CC=C3)C(=O)N
URB597是脂肪酸酰胺水解酶(FAAH)的相对选择性抑制剂。
Targets
FAAH
4.6 nM
In vitro (25°C) DMSO 62 mg/mL (183.21 mM)
Water Insoluble
Ethanol 5 mg/mL (14.77 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.55 mL 147.75 mL 295.51 mL
0.5 mM 5.91 mL 29.55 mL 59.1 mL
1 mM 2.96 mL 14.78 mL 29.55 mL
5 mM 0.59 mL 2.96 mL 5.91 mL

*The above data is based on the productmolecular weight 338.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.