Fosaprepitant dimeglumine

Catalog No. A11069

Fosaprepitant是一种选择性的神经激肽-1（NK-1）受体拮抗剂。

Technical details

Catalog Num	A11069
M. Wt	1004.84
Formula	C37H56F7N6O16P
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	265121-04-8
Synonyms	MK 0517
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O

Biological Activity

Fosaprepitant是一种选择性的神经激肽-1（NK-1）受体拮抗剂。

Targets

NK-1 receptor

Solubility *

In vitro	DMSO	183 mg/mL (182.12 mM)
	Water	123 mg/mL (122.41 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	9.95 mL	49.76 mL	99.52 mL
0.5 mM	1.99 mL	9.95 mL	19.9 mL
1 mM	1 mL	4.98 mL	9.95 mL
5 mM	0.2 mL	1 mL	1.99 mL

*The above data is based on the productmolecular weight 1004.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.