ADL5859 HCl

Catalog No. A11072

ADL5859 HCl是高效的选择性δ阿片受体激动剂，Ki值为0.84 nM，ED50值为20 nM。

Technical details

Catalog Num	A11072
M. Wt	429
Formula	C24H28N2O3.HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	850173-95-4
Synonyms	ADL-5859
SMILES	CCN(CC)C(=O)C1=CC=C(C=C1)C2=CC3(CCNCC3)OC4=C2C(=CC=C4)O.Cl

Biological Activity

ADL5859 HCl是高效的选择性δ阿片受体激动剂，Ki值为0.84 nM，ED50值为20 nM。

Targets

δ-opioid receptor	μ-opioid receptor	κ-opioid receptor
0.8 nM(Ki)	32 nM(Ki)	37 nM(Ki)

Solubility *

In vitro (25°C)	DMSO	76 mg/mL (177.17 mM)
	Water	4 mg/mL (9.32 mM)
	Ethanol	1 mg/mL (2.33 mM)
In vivo	0.5% hydroxyethyl cellulose+0.1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.31 mL	116.55 mL	233.1 mL
0.5 mM	4.66 mL	23.31 mL	46.62 mL
1 mM	2.33 mL	11.66 mL	23.31 mL
5 mM	0.47 mL	2.33 mL	4.66 mL

*The above data is based on the productmolecular weight 429. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.