Bosentan

Catalog No. A11091

Bosentan是内皮素-1(ET-A)和内皮素B(ET-B)受体的竞争性拮抗剂。
Catalog Num A11091
M. Wt 551.6
Formula C27H29N5O6S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 147536-97-8
Synonyms
SMILES CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC
Bosentan是内皮素-1(ET-A)和内皮素B(ET-B)受体的竞争性拮抗剂。
Targets
ET-A ET-B
4.7 nM(Ki)95 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.13 mL 90.65 mL 181.29 mL
0.5 mM 3.63 mL 18.13 mL 36.26 mL
1 mM 1.81 mL 9.06 mL 18.13 mL
5 mM 0.36 mL 1.81 mL 3.63 mL

*The above data is based on the productmolecular weight 551.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.