PHA-767491

Catalog No. A11164

PHA-767491是一种有效的,具有ATP竞争性的双重cdc7/cdk9抑制剂 (IC50值分别为10和34 nM),可防止DNA复制的启动。
  • Lei Tan, .et al. Homologous recombination technology generated recombinant pseudorabies virus expressing EGFP facilitates to evaluate its susceptibility to different cells and screen antiviral compounds, Res Vet Sci, 2022, 145: 125-134 PMID: 35190327
  • Qi Li, .et al. CDC7-dependent transcriptional regulation of RAD54L is essential for tumorigenicity and radio-resistance of glioblastoma, Transl Oncol, 2018, Apr; 11(2): 300-306 PMID: 29413763
Catalog Num A11164
M. Wt 213.24
Formula C12H11N3O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 845714-00-3
Synonyms PHA767491
SMILES C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3
PHA-767491是一种有效的,具有ATP竞争性的双重cdc7/cdk9抑制剂 (IC50值分别为10和34 nM),可防止DNA复制的启动。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 46.9 mL 234.48 mL 468.96 mL
0.5 mM 9.38 mL 46.9 mL 93.79 mL
1 mM 4.69 mL 23.45 mL 46.9 mL
5 mM 0.94 mL 4.69 mL 9.38 mL

*The above data is based on the productmolecular weight 213.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.