5-hydroxymethyl tolterodine (PNU 200577)

Catalog No. A11166

5-hydroxymethyl tolterodine (PNU 200577)是托特罗定的代谢产物，tolterodine是一种用于治疗尿失禁的毒蕈碱受体拮抗剂。

Technical details

Catalog Num	A11166
M. Wt	341.49
Formula	C22H31NO2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	207679-81-0
Synonyms	(R)-5-Hydroxymethyl tolterodine
SMILES	CC(C)N(CC[C@H](C1=CC=CC=C1)C2=C(C=CC(=C2)CO)O)C(C)C

Biological Activity

5-hydroxymethyl tolterodine (PNU 200577)是托特罗定的代谢产物，tolterodine是一种用于治疗尿失禁的毒蕈碱受体拮抗剂。

Targets

mAChR
0.84 nM(Kb)

Solubility *

In vitro	DMSO	60 mg/mL (175.69 mM)
	Water	Insoluble
	Ethanol	60 mg/mL (175.69 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.28 mL	146.42 mL	292.83 mL
0.5 mM	5.86 mL	29.28 mL	58.57 mL
1 mM	2.93 mL	14.64 mL	29.28 mL
5 mM	0.59 mL	2.93 mL	5.86 mL

*The above data is based on the productmolecular weight 341.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.