KX2-391

Catalog No. A11177

KX2-391是新型的非ATP竞争底物口袋定向SRC抑制剂。

Technical details

Catalog Num	A11177
M. Wt	431.53
Formula	C26H29N3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	897016-82-9
Synonyms	KX2391
SMILES	C1COCCN1CCOC2=CC=C(C=C2)C3=CN=C(C=C3)CC(=O)NCC4=CC=CC=C4

Biological Activity

KX2-391是新型的非ATP竞争底物口袋定向SRC抑制剂。

Targets

Src (HuH7) (Cell-free assay)	Src (PLC/PRF/5) (Cell-free assay)	Src (Hep 3B) (Cell-free assay)	Src (Hep G2) (Cell-free assay)
9 nM(GI50)	13 nM(GI50)	26 nM(GI50)	60 nM(GI50)

Solubility *

In vitro (25°C)	DMSO	77 mg/mL (178.43 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.17 mL	115.87 mL	231.73 mL
0.5 mM	4.63 mL	23.17 mL	46.35 mL
1 mM	2.32 mL	11.59 mL	23.17 mL
5 mM	0.46 mL	2.32 mL	4.63 mL

*The above data is based on the productmolecular weight 431.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.