PF-3845

Catalog No. A11183

PF-3845是一种有效的，选择性的，不可逆的FAAH抑制剂，Ki为230 nM。

Technical details

Catalog Num	A11183
M. Wt	456.46
Formula	C24H23F3N4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1196109-52-0
Synonyms	PF3845
SMILES	C1CN(CCC1CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=CN=CC=C4

Biological Activity

PF-3845是一种有效的，选择性的，不可逆的FAAH抑制剂，Ki为230 nM。

Targets

FAAH
230 nM(Ki)

Solubility *

In vitro (25°C)	DMSO	87 mg/mL (190.6 mM)
	Water	Insoluble
	Ethanol	87 mg/mL (190.6 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.91 mL	109.54 mL	219.08 mL
0.5 mM	4.38 mL	21.91 mL	43.82 mL
1 mM	2.19 mL	10.95 mL	21.91 mL
5 mM	0.44 mL	2.19 mL	4.38 mL

*The above data is based on the productmolecular weight 456.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.