PNU-120596

Catalog No. A11203

PNU-120596是α7神经元烟碱型乙酰胆碱受体的正变构调节剂。

Technical details

Catalog Num	A11203
M. Wt	311.72
Formula	C13H14ClN3O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	501925-31-1
Synonyms	PNU120596
SMILES	CC1=CC(=NO1)NC(=O)NC2=CC(=C(C=C2OC)OC)Cl

Biological Activity

PNU-120596是α7神经元烟碱型乙酰胆碱受体的正变构调节剂。

Targets

α7 nAChR
216 nM(EC50)

Solubility *

In vitro (25°C)	DMSO	53 mg/mL (170.02 mM)
	Water	Insoluble
	Ethanol	1 mg/mL (3.2 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.08 mL	160.4 mL	320.8 mL
0.5 mM	6.42 mL	32.08 mL	64.16 mL
1 mM	3.21 mL	16.04 mL	32.08 mL
5 mM	0.64 mL	3.21 mL	6.42 mL

*The above data is based on the productmolecular weight 311.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.